Surface contamination with nine antineoplastic drugs in 109 Canadian centers; 10 years of a monitoring program

Journal of Oncology Pharmacy Practice – A cross-sectional antineoplastic monitoring program is conducted once a year with voluntary Canadian hospital centers, since 2010. Twelve standardized sampling sites were sampled in 109 hospital centers between January 31 and June 18, 2020. Cyclophosphamide and gemcitabine were the drugs most frequently quantified on the surfaces. The armrest of patient treatment chairs, the front grille inside the biological safety cabinet (BSC) and the floor in front of the BSC were frequently contaminated. This large-scale study showed reproducible long term follow up of the contamination of standardized sites of Canadian centers and a reduction in surface contamination from 2010 to 2020.

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