International Journal of Molecular Sciences – In this review, researchers summarize and discuss the evidence regarding the effect of particulate matter (PM) and its impact in carcinogenesis, considering the “hallmarks of cancer” including sustained proliferative signaling, evasion of growth suppression, resistance to cell death, acquisition of replicative immortality, angiogenesis induction, and activation of invasion and metastasis. They found that exposure to particulate matter induces multiple hallmarks of cancer seen during tumor development.
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